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Report Card on provincial formulary
reimbursement listings for biologic response modifiers

Arthritis Consumer Experts (ACE) ranks publicly funded medication formularies based on the number of medically necessary arthritis medications (biologic response modifiers or "biologics") they list out of a possible eight.

Biologics are the gold standard in treatment for rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, and psoriatic arthritis.

Formularies are awarded one point for each case-by-case (CBC) listing, three-quarters of a point for a listing that has overly restrictive criteria (ORC), and no points for declined listings or files remaining "under review". In some cases, information about a medication was unavailable. Where this lack of transparency occurred, ACE put "Unknown" and did not award any points.

People with arthritis, with the help of the doctors who treat them, deserve to be able to choose the medication most appropriate for their specific risk factors. If after reading the Report Card you are disappointed with your province's performance, consider making your provincial government aware of your concerns. For tips on how to communicate with elected officials or key decision-makers, please visit our "What You Can Do" page within the "Taking Action" section of the JointHealth™ website.

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Biologic Chart : November 2011
1st : British Columbia
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Listed — CBC Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
2nd : Québec
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Under Review Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
2nd : Saskatchewan
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
4th : Alberta
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — ORC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — ORC Not Applicable Not Applicable Not Applicable
5th : New Brunswick
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Declined Listing Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Declined Listing
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
5th : Newfoundland and Labrador
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Declined Listing
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
5th : Ontario
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Under Review In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Listed — CBC Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Declined Listing
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
8th : Nova Scotia
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Under Review Not Applicable Declined Listing
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
8th : Prince Edward Island
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Listed — CBC Not Applicable Under Review
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Under Review Not Applicable Not Applicable Not Applicable
8th : NIHB*
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Listed — CBC In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Declined Listing Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Listed — CBC Listed — CBC
golimumab (Simponi®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
infliximab (Remicade®) Listed — CBC Declined Listing Not Applicable Declined Listing
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Listed — CBC Not Applicable Not Applicable Not Applicable
11th : Manitoba
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Under Review Not Applicable Under Review In Clinical Trials
adalimumab (Humira®) Listed — CBC Listed — CBC Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Listed — CBC Unknown Listed — CBC
golimumab (Simponi®) Under Review Under Review Not Applicable Under Review
infliximab (Remicade®) Listed — CBC Unknown Not Applicable Unknown
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Under Review Not Applicable Not Applicable Not Applicable
12th : Yukon
Generic Name (Brand Name) rheumatoid arthritis ankylosing spondylitis juvenile idiopathic arthritis psoriatic arthritis
abatacept (Orencia®) Listed — CBC Not Applicable Under Review In Clinical Trials
adalimumab (Humira®) Listed — CBC Under Review Not Applicable Listed — CBC
certolizumab pegol (Cimzia®) Under Review Not Applicable Not Applicable Not Applicable
etanercept (Enbrel®) Listed — CBC Under Review Unknown Under Review
golimumab (Simponi®) Under Review Under Review Not Applicable Under Review
infliximab (Remicade®) Listed — CBC Under Review Not Applicable Under Review
rituximab (Rituxan®) Listed — CBC Not Applicable Not Applicable Not Applicable
tocilizumab (Actemra®) Under Review Not Applicable Not Applicable Not Applicable

About the report card:
Arthritis Consumer Experts graded each of the provinces by assigning a score based upon number of medications listed, number under review, and number of declined listings. In some cases, information was unavailable from a province or territory's website. This lack of transparency was reflected in grade assignments.

Because provincial formularies change frequently, we encourage you to contact the Ministry of Health in your province with questions you may have about medication listings of concern to you.

Definitions

Declined Listing: The formulary does not reimburse patients prescribed this medication.
In Clinical Trials: This medication is undergoing testing for use in treating this disease type.
Listed - CBC: Each province and territory has a process by which medications that are not normally included in the provincial, territorial or federal drug benefit lists are covered (or reimbursed). Approval of this drug is granted on a case-by-case basis.
Listed - ORC: The medication is listed, but the criteria are not supported by medical evidence. Arthritis Consumer Experts considers these overly restrictive criteria (ORC) unacceptable.
NOC: A Notice of Compliance from Health Canada was issued for this medication for this form of arthritis. Notices of Compliance are issued for a medication when Health Canada is satisfied that the manufacturer has complied with certain sections of the Food and Drug Regulations.
Not Applicable: No Notice of Compliance (or NOC) has been issued for this medication for this form of arthritis.
Under Review: This drug has been approved by Health Canada for this disease type and the province is considering whether patients should be reimbursed for it.
Unknown: There is no public information available.
CDR: The Common Drug Review (CDR) is part of the Canadian Agency for Drugs and Technologies in Health. The Common Drug Review (CDR) conducts objective, rigorous reviews of the clinical and cost effectiveness of drugs, and provides formulary listing recommendations to the publicly funded drug plans in Canada (except Qu�bec). (http://cadth.ca/index.php//cdr)


* Note: People living in the Northwest Territories and Nunavut, who do not have private health insurance, have coverage for those drugs listed on the federal Non-Insured Health Benefits (NIHB) Formulary.